Role of pre-surgical breast MRI in the management of invasive breast carcinoma

Role of pre-surgical breast MRI in the management of invasive breast carcinoma
Chiara Del Frate, Ludovica Borghese, Carla Cedolini, Alexia Bestagno, Fabio Puglisi, Miriam Isola, Franca Soldano, Massimo Bazzocchi
TheBreast (2007) 16, 469 - 481
Abstract

Breast MRI determined an overall change in management in 22 out of 121 breasts (18.2%), and in two out of 87 breasts (25.3%) in patients eligible for conservative surgery. In the evaluation of single breasts, MRI resulted in true-positive in 22 out of 29 breasts (75.9%), false-positive in 7 out of 29 breasts (24.1%), leading to over-treatment in women whose treatment was changed from conservative surgery to radical mastectomy. MRI sensitivity in the detection of additional foci not seen on conventional imaging was 57.4%, overall sensitivity 87.4%, sensitivity for invasive cancers 93.1%, while for ductal carcinoma in situ it was 58.8%. In conclusion, breast MRI determines a significant change in the management of patients affected by invasive breast carcinoma, particularly in patients eligible for conservative surgery after standard breast examination